Dopamine infusion for the treatment of myocardial dysfunction associated with a persistent transitional circulation.
نویسندگان
چکیده
Four infants with myocardial dysfunction associated with a persistent transitional circulation were given dopamine infusions in addition to standard treatment. The condition of each improved strikingly with rapid diminution in heart size as judged by chest x-ray. Dopamine has a place in the management of the sick infant with a persistent transitional circulation.
منابع مشابه
P139: Role of Dopamine Receptor D3 in Depression and Anxiety
Dopamine (DA) is one of the main catecholamines in the brain and is crucial for movement coordination, endocrine function, reward, mood, memory and emotions. The dopaminergic system is the primary therapeutic target in the treatment of Parkinson’s disease (PD), drug addiction and schizophrenia. Notwithstanding, dysfunction of central dopaminergic neurotransmission has also been associated to de...
متن کاملCombined dopamine and nitroprusside therapy in congestive heart failure. Greater augmentation of cardiac performance by addition of inotropic stimulation to afterload reduction.
The hemodynamic benefits of combining administration of dopamine with nitroprusside (NP) were evaluated in nine patients with chronic congestive heart failure due to ischemic, idiopathic myocardial or valvular cardiac disease. NP alone (68 microng/min) produced decline in left ventricular end-diastolic pressure (LVEDP) from 25.4 to 14.1 mm Hg (p less than 0.01) but modest increase in cardiac in...
متن کاملCatecholamine stimulation, substrate competition, and myocardial glucose uptake in conscious dogs assessed with positron emission tomography.
Uptake of radiolabelled deoxyglucose out of proportion to reduced coronary flow demonstrated by positron emission tomography has been used to identify reversibly ischemic, viable myocardium. For this concept to be applied reliably in the clinical setting, factors that may depress glucose availability independent of tissue viability, such as adrenergic stimulation and substrate competition, must...
متن کاملDopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling.
BACKGROUND Ischemia and adrenergic stimulation of cardiomyocyte cultures have been shown to induce apoptotic cell death. We hypothesized that in a model of contractile dysfunction following ischemia, a commonly used catecholamine such as dopamine augments cardiomyocyte apoptosis via activation of calcium-dependent signaling cascades. METHODS AND RESULTS Isolated perfused rabbit hearts were su...
متن کاملPersistent hyperglycemia is associated with left ventricular dysfunction in patients with acute myocardial infarction.
BACKGROUND The relationship of changes in blood glucose concentrations after admission to left ventricular (LV) dysfunction in patients with recanalized anterior acute myocardial infarction (AMI) remains unclear. METHODS AND RESULTS Blood glucose concentrations were measured on admission and 24 h after symptom onset in 210 patients with recanalized anterior AMI within 6 h of symptom onset. Of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 55 3 شماره
صفحات -
تاریخ انتشار 1980